Trional

Trional

Systematic (IUPAC) name
2,2-bis(ethylsulfonyl)butane
Clinical data
Legal status	US: Schedule III
Identifiers
CAS Number	76-20-0
ATC code	None
PubChem	CID 6433
ChemSpider	6193
UNII	217727W28W
Chemical data
Formula	C8H18O4S2
Molar mass	242.356 g/mol
SMILES CCC(C)(S(=O)(=O)CC)S(=O)(=O)CC
InChI InChI=1S/C8H18O4S2/c1-5-8(4,13(9,10)6-2)14(11,12)7-3/h5-7H2,1-4H3 Key:LKACJLUUJRMGFK-UHFFFAOYSA-N
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Trional (Methylsulfonal) is a sedative-hypnotic^[1] and anesthetic drug with GABAergic actions. It has similar effects to sulfonal, except it is faster acting.^[2]

History

Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.^[3]

Appeared in Agatha Christie's "Murder On The Orient Express", "And Then There Were None" and other novels as a sleep inducing sedative, and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as an hypnotic.

See also

• Sulfonal
• Tetronal

References

1. (1907). Merck's 1907 Index. N. Y.: Merck & Co., p. 448.
2. Sajous, Charles E. (1896). Annual of the Universal Medical Sciences
   Philadelphia: F. A. Davis, v. 5, p. A-156.
3. Drinkwater, H. (1924). Fifty years of medical progress, 1873-1922.
   New York: The Macmillan Company, p. 40.