dbCRID

dbCRID

Content
Description	chromosomal rearrangements in human diseases.
Organisms	Homo sapiens
Contact
Laboratory	Biolead.org Research Group, LC Science
Authors	Fanlou Kong
Primary citation	Kong & al. (2011)^[1]
Release date	2010
Access
Website	http://dbCRID.biolead.org

The Chromosomal Rearrangements In Diseases (dbCRID) is a database of human chromosome rearrangements events and diseases related to them.^[1]

References

1 2 Kong, Fanlou; Zhu Jing; Wu Jun; Peng Jianjian; Wang Ying; Wang Qing; Fu Songbin; Yuan Li-Lian; Li Tongbin (Jan 2011). "dbCRID: a database of chromosomal rearrangements in human diseases". Nucleic Acids Res. (England) 39 (Database issue): D895–900. doi:10.1093/nar/gkq1038. PMC 3013658. PMID 21051346.

External links

http://dbCRID.biolead.org

Cytogenetics: chromosomes

Basic
concepts

Types

Autosome/Sex chromosome (or allosome or heterosome)
Macrochromosome/Microchromosome
Circular chromosome/Linear chromosome
Extra chromosome (or accessory chromosome)
Supernumerary chromosome
A chromosome/B chromosome
Lampbrush chromosome
Polytene chromosome
Dinoflagellate chromosomes
Homologous chromosome
Isochromosome
Satellite chromosome
Centromere position
Centromere number
- Acentric
- Monocentric
- Dicentric
- Polycentric

Processes
and evolution

Structures

Histone	H1 H2A H2B H3 H4

Centromere	A B C1 C2 E F H I J K M N O P Q T

See also

Extrachromosomal DNA
- Plasmid
List of organisms by chromosome count
List of chromosome lengths for various organisms
List of sequenced genomes

Chromosome abnormalities (Q90–Q99, 758)

Autosomal

Trisomies	Down syndrome 21 Edwards syndrome 18 Patau syndrome 13 Trisomy 9 Warkany syndrome 2 8 Cat eye syndrome/Trisomy 22 22 Trisomy 16

Monosomies/deletions	1q21.1 deletion syndrome/1q21.1 duplication syndrome/TAR syndrome 1 Wolf–Hirschhorn syndrome 4 Cri du chat/Chromosome 5q deletion syndrome 5 Williams syndrome 7 Jacobsen syndrome 11 Miller–Dieker syndrome/Smith–Magenis syndrome 17 DiGeorge syndrome 22 22q11.2 distal deletion syndrome 22 22q13 deletion syndrome 22 genomic imprinting Angelman syndrome/Prader–Willi syndrome (15) Distal 18q-/Proximal 18q-

X/Y linked

Monosomy	Turner syndrome (45,X)

Trisomy/tetrasomy, other karyotypes/mosaics	Klinefelter syndrome (47,XXY) 48,XXYY 48,XXXY 49,XXXYY 49,XXXXY Triple X syndrome (47,XXX) 48,XXXX 49,XXXXX 47,XYY 48,XYYY 49,XYYYY 45,X/46,XY

Translocations

Leukemia/lymphoma

Lymphoid	Burkitt's lymphoma t(8 MYC;14 IGH) Follicular lymphoma t(14 IGH;18 BCL2) Mantle cell lymphoma/Multiple myeloma t(11 CCND1:14 IGH) Anaplastic large-cell lymphoma t(2 ALK;5 NPM1) Acute lymphoblastic leukemia

Myeloid	Philadelphia chromosome t(9 ABL; 22 BCR) Acute myeloblastic leukemia with maturation t(8 RUNX1T1;21 RUNX1) Acute promyelocytic leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MKL1)

Other

Ewing's sarcoma t(11 FLI1; 22 EWS)
Synovial sarcoma t(x SYT;18 SSX)
Dermatofibrosarcoma protuberans t(17 COL1A1;22 PDGFB)
Myxoid liposarcoma t(12 DDIT3; 16 FUS)
Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS)
Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)

Other

This article is issued from Wikipedia - version of the Friday, April 29, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.