Interleukin-15 receptor

interleukin 15 receptor, alpha
Identifiers
Symbol IL15RA
Entrez 3601
HUGO 5978
OMIM 601070
RefSeq NM_172200
UniProt Q13261
Other data
Locus Chr. 10 p15-10p14
interleukin 2 receptor, beta
Identifiers
Symbol IL2RB
Alt. symbols CD122
Entrez 3560
HUGO 6009
OMIM 146710
RefSeq NM_000878
UniProt P14784
Other data
Locus Chr. 22 q13
interleukin 2 receptor, gamma (severe combined immunodeficiency)
Identifiers
Symbol IL2RG
Alt. symbols SCIDX1, IMD4
Entrez 3561
HUGO 6010
OMIM 308380
RefSeq NM_000206
Other data
Locus Chr. X q13

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[1]

References

  1. Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA (1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. doi:10.1074/jbc.270.50.29862. PMID 8530383.

External links


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