Interleukin-12 receptor

interleukin 12 receptor, beta 1
Identifiers
Symbol	IL12RB1
Alt. symbols	IL12RB, CD212
Entrez	3594
HUGO	5971
OMIM	601604
RefSeq	NM_005535
UniProt	P42701
Other data
Locus	Chr. 19 p13.1

beta 2 subunit, interleukin 12 receptor, beta 2
Identifiers
Symbol	IL12RB2
Entrez	3595
HUGO	5972
OMIM	601642
RefSeq	NM_001559
UniProt	Q99665
Other data
Locus	Chr. 1 p31.3-31.2

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12. It consists of beta 1^[1] and beta 2 subunits.^[2]

References

1. Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. PMID 7911493.
2. Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. doi:10.1073/pnas.93.24.14002. PMC 19484. PMID 8943050.

External links

• Receptors, Interleukin-12 at the US National Library of Medicine Medical Subject Headings (MeSH)