Multiple inositol-polyphosphate phosphatase

multiple inositol-polyphosphate phosphatase
Identifiers
EC number 3.1.3.62
CAS number 116958-30-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a multiple inositol-polyphosphate phosphatase (EC 3.1.3.62) is an enzyme that catalyzes the chemical reaction

myo-inositol hexakisphosphate + H2O \rightleftharpoons myo-inositol pentakisphosphate (mixed isomers) + phosphate

Thus, the two substrates of this enzyme are myo-inositol hexakisphosphate and H2O, whereas its two products are myo-inositol pentakisphosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 1D-myo-inositol-hexakisphosphate 5-phosphohydrolase. Other names in common use include inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase, inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase, inositol tetrakisphosphate phosphomonoesterase, inositol-1,3,4,5-tetrakisphosphate 3-phosphatase, and MIPP. This enzyme participates in inositol phosphate metabolism.

References

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