GNG7

Guanine nucleotide binding protein (G protein), gamma 7
Identifiers
Symbols	GNG7 ; FLJ00058
External IDs	OMIM: 604430 MGI: 95787 HomoloGene: 31293 GeneCards: GNG7 Gene
Gene ontology Molecular function • signal transducer activity Cellular component • heterotrimeric G-protein complex • plasma membrane • extracellular exosome Biological process • behavioral fear response • energy reserve metabolic process • receptor guanylyl cyclase signaling pathway • G-protein coupled receptor signaling pathway • synaptic transmission • locomotory behavior • regulation of G-protein coupled receptor protein signaling pathway • small molecule metabolic process • cellular response to glucagon stimulus Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2788	14708
Ensembl	ENSG00000176533	ENSMUSG00000048240
UniProt	O60262	Q61016
RefSeq (mRNA)	NM_052847	NM_001038655
RefSeq (protein)	NP_443079	NP_001033744
Location (UCSC)	Chr 19: 2.51 – 2.7 Mb	Chr 10: 80.95 – 81.01 Mb
PubMed search

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 is a protein that in humans is encoded by the GNG7 gene.^[1][2]

Interactions

GNG7 has been shown to interact with GNB5.^[3]

References

1. Shibata K, Mori M, Tanaka S, Kitano S, Akiyoshi T (Jun 1998). "Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer". Biochem. Biophys. Res. Commun. 246 (1): 205–9. doi:10.1006/bbrc.1998.8581. PMID 9600093.
2. "Entrez Gene: GNG7 guanine nucleotide binding protein (G protein), gamma 7".
3. Yan K, Kalyanaraman V, Gautam N (Mar 1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.

Further reading

• Ueda N, Iñiguez-Lluhi JA, Lee E, Smrcka AV, Robishaw JD, Gilman AG (1994). "G protein beta gamma subunits. Simplified purification and properties of novel isoforms". J. Biol. Chem. 269 (6): 4388–95. PMID 8308009.
• Yan K, Kalyanaraman V, Gautam N (1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.