Small nucleolar RNA F1/F2/snoR5a

Small nucleolar RNA F1/F2/snoR5a
Predicted secondary structure and sequence conservation of snoF1_F2
Identifiers
Symbol	snoF1_F2
Rfam	RF00482
Other data
RNA type	Gene; snRNA; snoRNA; HACA-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0000594

Small nucleolar RNA F1/F2/snoR5a refers to a group of related non-coding RNA (ncRNA) molecules which function in the biogenesis of other small nuclear RNAs (snRNAs). These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

These three snoRNas identified in rice (Oryza sativa), called F1, F2 and snoR5a, belong to the H/ACA box class of snoRNAs as they have the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. The majority of H/ACA box class of snoRNAs are involved in guiding the modification of uridine) to pseudouridine in other RNAs^[1]

References

1. .Kiss T (2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell 109 (2): 145–8. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400.

External links

• Page for Small nucleolar RNA F1/F2/snoR5a at Rfam