Small nucleolar RNA SNORD21

Small nucleolar RNA SNORD21
Predicted secondary structure and sequence conservation of SNORD21
Identifiers
Symbol	SNORD21
Alt. Symbols	U21
Rfam	RF00068
Other data
RNA type	Gene; snRNA; snoRNA; CD-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0000593

U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals,^[1] but within introns of the ADP ribosylation factor gene in Drosophila.^[2] U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.

References

1. Qu, LH; Nicoloso M; Michot B; Azum MC; Caizergues-Ferrer M; Renalier MH; Bachellerie JP (1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Res 22 (20): 4073–4081. doi:10.1093/nar/22.20.4073. PMC 331892. PMID 7937132.
2. [2] Renalier, MH; Nicoloso M; Qu LH; Bachellerie JP (1996). "SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates". FEBS Lett 379 (3): 212–216. doi:10.1016/0014-5793(95)01511-6. PMID 8603691.

External links

• Page for Small nucleolar RNA SNORD21 at Rfam