Small nucleolar RNA Me28S-Cm788

Small nucleolar RNA Me28S-Cm788
Predicted secondary structure and sequence conservation of snoMe28S-Cm788
Identifiers
Symbol snoMe28S-Cm788
Rfam RF00539
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000593

Small nucleolar RNA Me28S-Cm788 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me28S-Cm788 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1] This family is predicted to direct the 2'-O-methylation of 28S C-788.[2]

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