A-41988

A-41988

Systematic (IUPAC) name
8-[5-(4-fluorophenyl)pentan-2-yl]-5,5-dimethyl-2-prop-2-ynyl-3,4-dihydro-1H-chromeno[4,3-c]pyridin-10-ol
Identifiers
CAS Number	52763-30-1
PubChem	CID 3085018
ChemSpider	2341998
ChEMBL	CHEMBL303312
Chemical data
Formula	C28H32FNO2
Molar mass	433.556 g/mol
SMILES c4cc(F)ccc4CCCC(C)c3cc(O)c1C=2CN(CC#C)CCC=2C(C)(C)Oc1c3
InChI InChI=1S/C28H32FNO2/c1-5-14-30-15-13-24-23(18-30)27-25(31)16-21(17-26(27)32-28(24,3)4)19(2)7-6-8-20-9-11-22(29)12-10-20/h1,9-12,16-17,19,31H,6-8,13-15,18H2,2-4H3 Key:UIDOJGIFVOOMLY-UHFFFAOYSA-N
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A-41988 (BW29Y) is an analgesic drug which acts as a cannabinoid agonist. It was developed by Abbott Laboratories in the 1970s,^[1][2] and researched for potential use in the treatment of glaucoma,^[3] but never commercialised.

See also

• A-40174
• Menabitan

References

1. Winn, M.; Arendsen, D.; Dodge, P.; Dren, A.; Dunnigan, D.; Hallas, R.; Hwang, K.; Kyncl, J.; Lee, Y. H.; Plotnikoff, N.; Young, P.; Zaugg, H. (1976). "Drugs derived from cannabinoids. 5. Delta6a,10a-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains". Journal of Medicinal Chemistry 19 (4): 461–471. doi:10.1021/jm00226a003. PMID 817021.
2. Guterman A, Somani P, Bachand RT. Clinical Pharmacology and Therapeutics 1979; 25:227.
3. Tiedeman, J. S.; Shields, M. B.; Weber, P. A.; Crow, J. W.; Cocchetto, D. M.; Harris, W. A.; Howes, J. F. (1981). "Effect of synthetic cannabinoids on elevated intraocular pressure". Ophthalmology 88 (3): 270–277. doi:10.1016/s0161-6420(81)35052-0. PMID 7015221.