AM-087
 | |
| Systematic (IUPAC) name | |
|---|---|
|
(6aR,10aR)-3-(2-methyl-6-bromohex-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol | |
| Identifiers | |
| CAS Number |
152674-96-9  |
| PubChem | CID 10717065 |
| ChemSpider |
8892405 |
| ChEMBL |
CHEMBL199561 |
| Chemical data | |
| Formula | C23H33BrO2 |
| Molar mass | 421.410 g/mol |
| |
| |
| (verify) | |
AM-087 (part of the AM cannabinoid series) is an analgesic drug which acts as a cannabinoid agonist.[1] It is a derivative of Δ8THC substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43nM, making it around 100x more potent than THC itself. This is most likely due to the bulky bromine substituent on the side chain.[2]
See also
References
- ↑ Martin, Billy R.; Compton, David R.; Semus, Simon F.; Lin, Sonyuan; Marciniak, Gilbert; Grzybowska, Jolanta; Charalambous, Avgui; Makriyannis, Alexandros (1993). "Pharmacological evaluation of iodo and nitro analogs of Δ8-THC and Δ9-THC". Pharmacology Biochemistry and Behavior 46 (2): 295–301. doi:10.1016/0091-3057(93)90356-X. ISSN 0091-3057.
- ↑ Charalambous A, et al. Pharmacological evaluation of halogenated delta 8-THC analogs. Pharmacology, Biochemistry and Behaviour. 1991 Nov;40(3):509-12. PMID 1666915
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