HU-243
 | |
| Systematic (IUPAC) name | |
|---|---|
|
(6aR,8S,9S,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-8,9-ditritio-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-1-ol | |
| Identifiers | |
| CAS Number |
140835-18-3  |
| PubChem | CID 3081854 |
| IUPHAR/BPS | 735 |
| Chemical data | |
| Formula | C25H40O3 |
| Molar mass | 388.30 g/mol |
| |
HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a potent agonist at both the CB1 and CB2 receptors, with a binding affinity of 0.041nM at the CB1 receptor, making it marginally more potent than HU-210, which had an affinity of 0.061nM in the same assay.[1]
See also
References
- ↑ Stern, E.; Lambert, D. M. (2007). "Medicinal Chemistry Endeavors around the Phytocannabinoids". Chemistry & Biodiversity 4 (8): 1707–1728. doi:10.1002/cbdv.200790149. PMID 17712816.
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