O-1125

O-1125

Systematic (IUPAC) name
6-[(6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]-N,N,6-trimethylheptanamide
Identifiers
PubChem	CID 9909689
ChemSpider	8085340
Chemical data
Formula	C26H39NO3
Molar mass	413.591 g/mol
SMILES CC1=CC[C@@H]2[C@@H](C1)C3=C(C=C(C=C3OC2(C)C)C(C)(C)CCCCC(=O)N(C)C)O
InChI InChI=1S/C26H39NO3/c1-17-11-12-20-19(14-17)24-21(28)15-18(16-22(24)30-26(20,4)5)25(2,3)13-9-8-10-23(29)27(6)7/h11,15-16,19-20,28H,8-10,12-14H2,1-7H3/t19-,20-/m1/s1 Key:QGBHDXFADXCURB-WOJBJXKFSA-N
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O-1125 (3-(1,1-dimethylhexyl-6-dimethylcarboxamide)-Δ8-tetrahydrocannabinol) is a drug which is a cannabinoid derivative. It has analgesic effects and is used in scientific research. It is a potent CB₁ full agonist with a Ki of 1.16nM.^[1]

References

1. Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 1999 Oct;128(3):684-8. doi:10.1038/sj.bjp.0702806 PMID 10516649