HTR3D

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
Identifiers
Symbols	HTR3D ; 5HT3D
External IDs	OMIM: 610122 HomoloGene: 52320 IUPHAR: 376 ChEMBL: 4673 GeneCards: HTR3D Gene
Gene ontology Molecular function • acetylcholine-activated cation-selective channel activity • serotonin receptor activity • serotonin-activated cation-selective channel activity • acetylcholine receptor activity • acetylcholine binding Cellular component • plasma membrane • acetylcholine-gated channel complex • neuron projection • synapse Biological process • serotonin receptor signaling pathway • synaptic transmission, cholinergic • neuromuscular synaptic transmission • ion transmembrane transport • response to nicotine • regulation of membrane potential • neurological system process • transmembrane transport • cation transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	200909	n/a
Ensembl	ENSG00000186090	n/a
UniProt	Q70Z44	n/a
RefSeq (mRNA)	NM_001145143	n/a
RefSeq (protein)	NP_001138615	n/a
Location (UCSC)	Chr 3: 184.03 – 184.04 Mb	n/a
PubMed search		n/a

5-hydroxytryptamine receptor 3D is a protein that in humans is encoded by the HTR3D gene.^[1][1] The protein encoded by this gene is a subunit of the 5-HT3 receptor.

References

1. Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3". Gene 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179.

External links

• HTR3D protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)