CXCL17

chemokine (C-X-C motif) ligand 7
Identifiers
Symbol	CXCL17
Alt. symbols	SCYB17, VCC-1, DMC
Entrez	284340
RefSeq	NM_198477
UniProt	Q6UXB2
Other data
Locus	Chr. 19 q13.2

Chemokine (C-X-C motif) ligand 17 (CXCL17) is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC).^[1][2] This chemokine is constitutively expressed in the lung.^[2] The gene for human CXCL17 is located on chromosome 19.^[2]

References

1. Weinstein E, Head R, Griggs D, Sun D, Evans R, Swearingen M, Westlin M, Mazzarella R (2006). "VCC-1, a novel chemokine, promotes tumor growth". Biochem Biophys Res Commun 350 (1): 74–81. doi:10.1016/j.bbrc.2006.08.194. PMID 16989774.
2. Pisabarro M, Leung B, Kwong M, Corpuz R, Frantz G, Chiang N, Vandlen R, Diehl L, Skelton N, Kim H, Eaton D, Schmidt K (2006). "Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods". J Immunol 176 (4): 2069–73. doi:10.4049/jimmunol.176.4.2069. PMID 16455961.