STYK1

Serine/threonine/tyrosine kinase 1
Identifiers
Symbols	STYK1 ; NOK; SuRTK106
External IDs	OMIM: 611433 MGI: 2141396 HomoloGene: 49545 GeneCards: STYK1 Gene
EC number	2.7.10.2
Gene ontology Molecular function • non-membrane spanning protein tyrosine kinase activity • receptor binding • protein binding • ATP binding Cellular component • plasma membrane • integral component of membrane • extrinsic component of cytoplasmic side of plasma membrane Biological process • transmembrane receptor protein tyrosine kinase signaling pathway • cell differentiation • peptidyl-tyrosine autophosphorylation • regulation of cell proliferation • innate immune response Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55359	243659
Ensembl	ENSG00000060140	ENSMUSG00000032899
UniProt	Q6J9G0	Q6J9G1
RefSeq (mRNA)	NM_018423	NM_172891
RefSeq (protein)	NP_060893	NP_766479
Location (UCSC)	Chr 12: 10.62 – 10.67 Mb	Chr 6: 131.3 – 131.35 Mb
PubMed search

Tyrosine-protein kinase STYK1 is an enzyme that in humans is encoded by the STYK1 gene.^[1][2]

References

1. Ye X, Ji C, Huang Q, Cheng C, Tang R, Xu J, Zeng L, Dai J, Wu Q, Gu S, Xie Y, Mao Y (Jul 2003). "Isolation and characterization of a human putative receptor protein kinase cDNA STYK1". Mol Biol Rep 30 (2): 91–6. doi:10.1023/A:1023934017174. PMID 12841579.
2. "Entrez Gene: STYK1 serine/threonine/tyrosine kinase 1".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liu L, Yu XZ, Li TS, et al. (2004). "A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice.". Cancer Res. 64 (10): 3491–9. doi:10.1158/0008-5472.CAN-03-2106. PMID 15150103.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Amachika T, Kobayashi D, Moriai R, et al. (2007). "Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers.". Lung Cancer 56 (3): 337–40. doi:10.1016/j.lungcan.2007.01.002. PMID 17298854.