Receptor tyrosine kinase-like orphan receptor
| receptor tyrosine kinase-like orphan receptor 1 | |
|---|---|
| Identifiers | |
| Symbol | ROR1 |
| Alt. symbols | NTRKR1 |
| Entrez | 4919 |
| HUGO | 10256 |
| OMIM | 602336 |
| RefSeq | NM_005012 |
| UniProt | Q01973 |
| Other data | |
| EC number | 2.7.10.1 |
| Locus | Chr. 1 p32-p31 |
| receptor tyrosine kinase-like orphan receptor 2 | |
|---|---|
| Identifiers | |
| Symbol | ROR2 |
| Alt. symbols | NTRKR2, BDB, BDB1 |
| Entrez | 4920 |
| HUGO | 10257 |
| OMIM | 602337 |
| RefSeq | NM_004560 |
| UniProt | Q01974 |
| Other data | |
| Locus | Chr. 9 q22 |
In the field of molecular biology, receptor tyrosine kinase-like orphan receptors (RORs) are a family of tyrosine kinase receptors that are important in regulating skeletal and neuronal development, cell migration and cell polarity. ROR proteins can modulate Wnt signaling by sequestering Wnt ligands.[1]
References
- ↑ Green JL, Kuntz SG, Sternberg PW (November 2008). "Ror receptor tyrosine kinases: orphans no more". Trends Cell Biol. 18 (11): 536–44. doi:10.1016/j.tcb.2008.08.006. PMID 18848778.
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