EMPA (drug)
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| Systematic (IUPAC) name | |
|---|---|
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N-Ethyl-N2-(6-methoxy-3-pyridinyl)-N2-[(2-methylphenyl)sulfonyl]-N-(3-pyridinylmethyl)glycinamide | |
| Identifiers | |
| CAS Number | 680590-49-2 |
| ATC code | none |
| PubChem | CID 9981404 |
| ChemSpider | 8156996 |
| Chemical data | |
| Formula | C23H26N4O4S |
| Molar mass | 454.542 g/mol |
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EMPA is a selective antagonist of the OX2 receptor, with 900-fold selectivity in binding for OX2 over OX1.[1][2]
See also
References
- ↑ "Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists", , Pari Malherbe, Edilio Borroni, Emmanuel Pinard, Joseph G. Wettstein, and Frederic Knoflach, in Molecular Pharmacology, , 2009
- ↑ Malherbe et al (2009) Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX2 receptor. Br.J.Pharmacol. 156 1326. PMID 19751316.
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