Vapreotide
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Systematic (IUPAC) name | |
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D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-tryptophanamide (2->7)-disulfide | |
Clinical data | |
Trade names | Sanvar |
Pharmacokinetic data | |
Biological half-life | 30 minutes |
Identifiers | |
CAS Number | 103222-11-3 |
ATC code | H01CB04 |
PubChem | CID 23725064 |
DrugBank | DB04894 |
ChemSpider | 64425 |
UNII | 2PK59M9GFF |
KEGG | D06281 |
Synonyms |
H-D-Phe-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Trp-NH2 Octastatin |
Chemical data | |
Formula | C57H70N12O9S2 |
Molar mass | 1131.37 g/mol |
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Physical data | |
Density | 1.4 g/cm3 |
Boiling point | 1,540.9 °C (2,805.6 °F) |
Vapreotide (Sanvar) is a synthetic somatostatin analog. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea.[1]
It is an 8 residue peptide with sequence H-D-Phe-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Trp-NH2.
References
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