Olcegepant
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| Systematic (IUPAC) name | |
|---|---|
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N-{(2S)-6-Amino-1-oxo-1-[4-(4-pyridinyl)-1-piperazinyl]-2-hexanyl}-3,5-dibromo-Nα-{[4-(2-oxo-1,4-dihydro-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl}-D-tyrosinamide | |
| Identifiers | |
| CAS Number | 204697-65-4 |
| ATC code | None |
| PubChem | CID 6918509 |
| ChemSpider | 5293706 |
| Chemical data | |
| Formula | C38H47Br2N9O5 |
| Molar mass | 869.645 g/mol |
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Olcegepant (INN) (code name BIBN-4096BS) is a calcitonin gene-related peptide receptor antagonist being studied as a potential treatment for migraines.[1]
A 2013 meta-analysis found olcegepant and telcagepant were effective and safe compared to placebo.[2]
See also
References
- ↑ Tfelt-Hansen, P; Olesen, J (Apr 2011). "Possible site of action of CGRP antagonists in migraine.". Cephalalgia : an international journal of headache 31 (6): 748–50. doi:10.1177/0333102411398403. PMID 21383046.
- ↑ Yao, Gang; Yu, Tingmin; Han, Ximei; Mao, Xijing; Li, Bo (2013-04-05). "Therapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis". Neural Regeneration Research 8 (10): 938–947. doi:10.3969/j.issn.1673-5374.2013.10.009. ISSN 1673-5374. PMC 4145922. PMID 25206386.
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