Neuromedin N

Neuromedin N^[1]

Identifiers
CAS Number	102577-25-3
IUPHAR/BPS	1578
Jmol interactive 3D	Image
PubChem	3025353
SMILES OC([C@H](CC(C)C)NC([C@@]([C@H](CC)C)([H])NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H]2CCCN2C([C@](NC([C@@H](N)CCCCN)=O)([H])[C@H](CC)C)=O)=O)=O)=O)=O
Properties
Chemical formula	C38H63N7O8
Molar mass	745.949
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Neuromedin N
Identifiers
Symbol	NN
Entrez	4922
HUGO	8038
Other data
Locus	Chr. 12 q21

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.^{[2][3][4][5][6][7]}

References

1. Neuromedin N - Compound Summary, PubChem.
2. Carraway RE, Mitra SP, Spaulding G (1992). "Posttranslational processing of the neurotensin/neuromedin-N precursor". Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 1–16. doi:10.1111/j.1749-6632.1992.tb27335.x. PMID 1463268.
3. Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). "Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N". Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 30–42. doi:10.1111/j.1749-6632.1992.tb27337.x. PMID 1463273.
4. Vincent JP (October 1995). "Neurotensin receptors: binding properties, transduction pathways, and structure". Cellular and Molecular Neurobiology 15 (5): 501–12. doi:10.1007/BF02071313. PMID 8719037.
5. Adams DH, Hanson GR, Keefe KA (2001). "Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum". Neuroscience 102 (4): 843–51. doi:10.1016/S0306-4522(00)00530-3. PMID 11182247.
6. Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (February 2002). "Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity". Biochemical and Biophysical Research Communications 290 (4): 1161–8. doi:10.1006/bbrc.2001.6308. PMID 11811984.
7. Kitabgi P (October 2006). "Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases". Peptides 27 (10): 2508–14. doi:10.1016/j.peptides.2006.03.038. PMID 16904237.