NCAPG2

Non-SMC condensin II complex, subunit G2
Identifiers
Symbols	NCAPG2 ; CAP-G2; CAPG2; LUZP5; MTB; hCAP-G2
External IDs	OMIM: 608532 MGI: 1923294 HomoloGene: 9820 GeneCards: NCAPG2 Gene
Gene ontology Molecular function • protein binding • methylated histone binding Cellular component • nucleus • nucleoplasm • membrane Biological process • mitotic cell cycle • inner cell mass cell proliferation • mitotic nuclear division • chromosome condensation • cell division Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54892	76044
Ensembl	ENSG00000146918	ENSMUSG00000042029
UniProt	Q86XI2	Q6DFV1
RefSeq (mRNA)	NM_001281932	NM_133762
RefSeq (protein)	NP_001268861	NP_598523
Location (UCSC)	Chr 7: 158.63 – 158.7 Mb	Chr 12: 116.41 – 116.46 Mb
PubMed search

Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene.^[1][2] CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References

1. Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (Oct 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
2. "Entrez Gene: NCAPG2 non-SMC condensin II complex, subunit G2".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Smith ED, Xu Y, Tomson BN, et al. (2004). "More than blood, a Novel Gene Required for Mammalian Postimplantation Development". Mol. Cell. Biol. 24 (3): 1168–73. doi:10.1128/MCB.24.3.1168-1173.2004. PMC 321451. PMID 14729962.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.