NCAPH2
Non-SMC condensin II complex, subunit H2 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | NCAPH2 ; CAPH2 | ||||||||||||
External IDs | OMIM: 611230 MGI: 1289164 HomoloGene: 12045 GeneCards: NCAPH2 Gene | ||||||||||||
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Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 29781 | 52683 | |||||||||||
Ensembl | ENSG00000025770 | ENSMUSG00000008690 | |||||||||||
UniProt | Q6IBW4 | Q8BSP2 | |||||||||||
RefSeq (mRNA) | NM_001185011 | NM_001115132 | |||||||||||
RefSeq (protein) | NP_001171940 | NP_001108604 | |||||||||||
Location (UCSC) |
Chr 22: 50.51 – 50.52 Mb |
Chr 15: 89.36 – 89.37 Mb | |||||||||||
PubMed search | |||||||||||||
Condensin-2 complex subunit H2, also known as chromosome-associated protein H2 (CAP-H2) or non-SMC condensin II complex subunit H2 (NCAPH2), is a protein that in humans is encoded by the NCAPH2 gene.[1] CAP-H2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.
References
Further reading
- Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.". Genomics 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
- Ono T, Losada A, Hirano M, et al. (2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.". Cell 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
- Talmud PJ, Drenos F, Shah S, et al. (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
- Wood AJ, Severson AF, Meyer BJ (2010). "Condensin and cohesin complexity: the expanding repertoire of functions.". Nat. Rev. Genet. 11 (6): 391–404. doi:10.1038/nrg2794. PMC 3491780. PMID 20442714.
- Schleiffer A, Kaitna S, Maurer-Stroh S, et al. (2003). "Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.". Mol. Cell 11 (3): 571–5. doi:10.1016/S1097-2765(03)00108-4. PMID 12667442.
- Kamatani Y, Matsuda K, Okada Y, et al. (2010). "Genome-wide association study of hematological and biochemical traits in a Japanese population.". Nat. Genet. 42 (3): 210–5. doi:10.1038/ng.531. PMID 20139978.
- Collins JE, Wright CL, Edwards CA, et al. (2004). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bailey SD, Xie C, Do R, et al. (2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.". Diabetes Care 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
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