SMC1B
| Structural maintenance of chromosomes 1B | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SMC1B ; SMC1BETA; SMC1L2 | ||||||||||||
| External IDs | OMIM: 608685 MGI: 2154049 HomoloGene: 13786 GeneCards: SMC1B Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 27127 | 140557 | |||||||||||
| Ensembl | ENSG00000077935 | ENSMUSG00000022432 | |||||||||||
| UniProt | Q8NDV3 | Q920F6 | |||||||||||
| RefSeq (mRNA) | NM_001291501 | NM_080470 | |||||||||||
| RefSeq (protein) | NP_001278430 | NP_536718 | |||||||||||
| Location (UCSC) |
Chr 22: 45.34 – 45.41 Mb |
Chr 15: 85.06 – 85.13 Mb | |||||||||||
| PubMed search | |||||||||||||
Structural maintenance of chromosomes protein 1B (SMC-1B) is a protein that in humans is encoded by the SMC1B gene.[1][2][3] SMC-1B belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis.[3]
References
- ↑ "Entrez Gene: structural maintenance of chromosomes 1B".
- ↑ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (December 1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
- 1 2 Revenkova E, Eijpe M, Heyting C, Gross B, Jessberger R (October 2001). "Novel meiosis-specific isoform of mammalian SMC1". Mol. Cell. Biol. 21 (20): 6984–98. doi:10.1128/MCB.21.20.6984-6998.2001. PMC 99874. PMID 11564881.
Further reading
- Zhang X, Yang H, Lee JJ, et al. (2010). "MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.". Carcinogenesis 31 (12): 2118–23. doi:10.1093/carcin/bgq177. PMC 3105587. PMID 20819778.
- Cobbe N, Heck MM (2004). "The evolution of SMC proteins: phylogenetic analysis and structural implications.". Mol. Biol. Evol. 21 (2): 332–47. doi:10.1093/molbev/msh023. PMID 14660695.
- Prieto I, Tease C, Pezzi N, et al. (2004). "Cohesin component dynamics during meiotic prophase I in mammalian oocytes.". Chromosome Res. 12 (3): 197–213. doi:10.1023/B:CHRO.0000021945.83198.0e. PMID 15125634.
- Lee J, Iwai T, Yokota T, Yamashita M (2003). "Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis.". J. Cell. Sci. 116 (Pt 13): 2781–90. doi:10.1242/jcs.00495. PMID 12759374.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome.". Mol. Cell Proteomics 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.
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