OR10A5

Olfactory receptor, family 10, subfamily A, member 5
Identifiers
Symbols	OR10A5 ; JCG6; OR10A1; OR11-403
External IDs	OMIM: 608493 MGI: 3030547 HomoloGene: 17470 GeneCards: OR10A5 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	144124	259036
Ensembl	ENSG00000166363	ENSMUSG00000073898
UniProt	Q9H207	Q496U7
RefSeq (mRNA)	NM_178168	NM_147034
RefSeq (protein)	NP_835462	NP_667245
Location (UCSC)	Chr 11: 6.85 – 6.85 Mb	Chr 7: 107.04 – 107.04 Mb
PubMed search

Olfactory receptor 10A5 is a protein that in humans is encoded by the OR10A5 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5".

Further reading

• Buettner JA, Glusman G, Ben-Arie N, et al. (1998). "Organization and evolution of olfactory receptor genes on human chromosome 11.". Genomics 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
• Lane RP, Cutforth T, Young J, et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci.". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679. PMID 11416212.
• Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library.". Chem. Senses 26 (9): 1157–66. doi:10.1093/chemse/26.9.1157. PMID 11705801.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR10A5 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.