OR1J4
Olfactory receptor, family 1, subfamily J, member 4 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | OR1J4 ; HSHTPCRX01; HTPCRX01; OR9-21 | ||||||||||||
External IDs | MGI: 3030184 HomoloGene: 64897 GeneCards: OR1J4 Gene | ||||||||||||
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Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 26219 | 258620 | |||||||||||
Ensembl | ENSG00000239590 | ENSMUSG00000050015 | |||||||||||
UniProt | Q8NGS1 | Q8VFP8 | |||||||||||
RefSeq (mRNA) | NM_001004452 | NM_146627 | |||||||||||
RefSeq (protein) | NP_001004452 | NP_666838 | |||||||||||
Location (UCSC) |
Chr 9: 122.52 – 122.52 Mb |
Chr 2: 36.85 – 36.85 Mb | |||||||||||
PubMed search | |||||||||||||
Olfactory receptor 1J4 is a protein that in humans is encoded by the OR1J4 gene.[1][2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
See also
References
- ↑ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J; et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
- 1 2 "Entrez Gene: OR1J4 olfactory receptor, family 1, subfamily J, member 4".
Further reading
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
External links
- OR1J4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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