OR51B5

Olfactory receptor, family 51, subfamily B, member 5
Identifiers
Symbols	OR51B5 ; HOR5'Beta5; OR11-37
External IDs	HomoloGene: 133898 GeneCards: OR51B5 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	282763	259126
Ensembl	ENSG00000242180	ENSMUSG00000055124
UniProt	Q9H339	n/a
RefSeq (mRNA)	NM_001005567	NM_147122
RefSeq (protein)	NP_001005567	NP_667333
Location (UCSC)	Chr 11: 5.34 – 5.34 Mb	Chr 7: 103.66 – 103.66 Mb
PubMed search

Olfactory receptor 51B5 is a protein that in humans is encoded by the OR51B5 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR51B5 olfactory receptor, family 51, subfamily B, member 5".

Further reading

• Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430.
• Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR51B5 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.