OR51M1

Olfactory receptor, family 51, subfamily M, member 1
Identifiers
Symbols	OR51M1 ; HOR5'Beta7; OR11-40
External IDs	MGI: 3030465 HomoloGene: 64935 GeneCards: OR51M1 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	390059	258961
Ensembl	ENSG00000184698	ENSMUSG00000042219
UniProt	Q9H341	F8VPJ9
RefSeq (mRNA)	NM_001004756	NM_001271020
RefSeq (protein)	NP_001004756	NP_001257949
Location (UCSC)	Chr 11: 5.39 – 5.39 Mb	Chr 7: 103.93 – 103.93 Mb
PubMed search

Olfactory receptor 51M1 is a protein that in humans is encoded by the OR51M1 gene.^[1]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.^[2] The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR51M1 olfactory receptor, family 51, subfamily M, member 1".
2. Knape K, Beyer A, Stary A, Buchbauer G, Wolschann P (2008). "Genomics of selected human odorant receptors". Chemical Monthly 139 (12): 1537–1544. doi:10.1007/s00706-008-0957-6.

Further reading

• Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430.
• Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR51M1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.