OR10J1

Olfactory receptor, family 10, subfamily J, member 1
Identifiers
Symbols	OR10J1 ; HGMP07J; HSHGMP07J
External IDs	MGI: 3030052 HomoloGene: 8218 GeneCards: OR10J1 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • odorant binding Cellular component • plasma membrane • integral component of plasma membrane Biological process • G-protein coupled receptor signaling pathway • single fertilization • sensory perception of chemical stimulus • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	26476	258645
Ensembl	ENSG00000196184	ENSMUSG00000049605
UniProt	P30954	Q8VG32
RefSeq (mRNA)	NM_012351	NM_146651
RefSeq (protein)	NP_036483	NP_666862
Location (UCSC)	Chr 1: 159.44 – 159.44 Mb	Chr 1: 173.27 – 173.27 Mb
PubMed search

Olfactory receptor 10J1 is a protein that in humans is encoded by the OR10J1 gene.^[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[2]

See also

• Olfactory receptor

References

1. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J; et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
2. "Entrez Gene: OR10J1 olfactory receptor, family 10, subfamily J, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR10J1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.