OR7C1

Olfactory receptor, family 7, subfamily C, member 1
Identifiers
Symbols	OR7C1 ; CIT-HSP-146E8; HSTPCR86P; OR19-5; OR7C4; TPCR86
External IDs	MGI: 3030704 HomoloGene: 131141 GeneCards: OR7C1 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • spermatogenesis • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	26664	259074
Ensembl	ENSG00000127530	ENSMUSG00000046493
UniProt	O76099	E9PWW1
RefSeq (mRNA)	NM_198944	NM_147071
RefSeq (protein)	NP_945182	NP_667282
Location (UCSC)	Chr 19: 14.8 – 14.8 Mb	Chr 10: 78.98 – 78.98 Mb
PubMed search

Olfactory receptor 7C1 is a protein that in humans is encoded by the OR7C1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR7C1 olfactory receptor, family 7, subfamily C, member 1".

Further reading

• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics 39 (3): 239–246. doi:10.1006/geno.1996.4490. PMID 9119360.
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome". Biochem. Biophys. Res. Commun. 237 (2): 283–287. doi:10.1006/bbrc.1997.7043. PMID 9268701.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR7C1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.