OR2A2

Olfactory receptor, family 2, subfamily A, member 2
Identifiers
Symbols	OR2A2 ; OR2A17P; OR2A2P; OR7-11; OST008
External IDs	MGI: 3030275 HomoloGene: 133887 GeneCards: OR2A2 Gene
Gene ontology Molecular function • transmembrane signaling receptor activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • detection of chemical stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	442361	258648
Ensembl	ENSG00000221989	ENSMUSG00000094200
UniProt	Q6IF42	Q8VFS4
RefSeq (mRNA)	NM_001005480	NM_146654
RefSeq (protein)	NP_001005480	NP_666865
Location (UCSC)	Chr 7: 144.11 – 144.11 Mb	Chr 6: 43.15 – 43.15 Mb
PubMed search

Olfactory receptor 2A2 is a protein that in humans is encoded by the OR2A2 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR2A2 olfactory receptor, family 2, subfamily A, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2A2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.