OR2S2

Olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
Identifiers
Symbols	OR2S2 ; OR37A; OST715
External IDs	HomoloGene: 84331 GeneCards: OR2S2 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	56656	29845
Ensembl	ENSG00000278889	ENSMUSG00000071000
UniProt	Q9NQN1	Q8R469
RefSeq (mRNA)	NM_019897	NM_019473
RefSeq (protein)	NP_063950	NP_062346
Location (UCSC)	Chr 9: 35.96 – 35.96 Mb	Chr 4: 43.85 – 43.86 Mb
PubMed search

Olfactory receptor 2S2 is a protein that in humans is encoded by the OR2S2 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR2S2 olfactory receptor, family 2, subfamily S, member 2".

Further reading

• Strotmann J, Hoppe R, Conzelmann S, et al. (1999). "Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization". Gene 236 (2): 281–91. doi:10.1016/S0378-1119(99)00275-9. PMID 10452948.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human". Genomics 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID 12906860.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR2S2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.