OR4S2

Olfactory receptor, family 4, subfamily S, member 2
Identifiers
Symbols	OR4S2 ; OR11-137; OR4S2P; OST725
External IDs	MGI: 3031027 HomoloGene: 27297 GeneCards: OR4S2 Gene
Gene ontology Molecular function • transmembrane signaling receptor activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • detection of chemical stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	219431	329460
Ensembl	ENSG00000174982	ENSMUSG00000060827
UniProt	Q8NH73	A2AV13
RefSeq (mRNA)	NM_001004059	NM_001011517
RefSeq (protein)	NP_001004059	NP_001011517
Location (UCSC)	Chr 11: 55.65 – 55.65 Mb	Chr 2: 88.68 – 88.68 Mb
PubMed search

Olfactory receptor 4S2 is a protein that in humans is encoded by the OR4S2 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. "Entrez Gene: OR4S2 olfactory receptor, family 4, subfamily S, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Gilad Y, Lancet D (2003). "Population differences in the human functional olfactory repertoire". Mol. Biol. Evol. 20 (3): 307–14. doi:10.1093/molbev/msg013. PMID 12644552.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4S2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.