Dyphylline

Dyphylline
Systematic (IUPAC) name
7-(2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Clinical data
Trade names Lufyllin
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a682494
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
Legal status
Identifiers
CAS Number 479-18-5 YesY
ATC code R03DA01 (WHO)
PubChem CID 3182
IUPHAR/BPS 7070
DrugBank DB00651 YesY
ChemSpider 3070 YesY
UNII 263T0E9RR9 YesY
KEGG D00691 YesY
ChEBI CHEBI:4728 YesY
ChEMBL CHEMBL1752 YesY
Synonyms 7-(2,3-dihydroxy-propyl)theophylline
Chemical data
Formula C10H14N4O4
Molar mass 254.24 g/mol
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Dyphylline (USAN) (trade names Dilor, Lufyllin), also known as diprophylline (INN), is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.[1][2]

See also

References

  1. Schwabe U, Ukena D, Lohse MJ (September 1985). "Xanthine derivatives as antagonists at A1 and A2 adenosine receptors". Naunyn-Schmiedeberg's Archives of Pharmacology 330 (3): 212–21. doi:10.1007/bf00572436. PMID 2997628.
  2. Iancu L, Shneur A, Cohen H (1979). "Trials with xanthine derivatives in systemic treatment of psoriasis". Dermatologica 159 (1): 55–61. doi:10.1159/000250562. PMID 225216.



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