MAST1

Microtubule associated serine/threonine kinase 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2M9X​, 3PS4​
Identifiers
Symbols	MAST1 ; SAST; SAST170
External IDs	OMIM: 612256 MGI: 1861901 HomoloGene: 10543 ChEMBL: 1163128 GeneCards: MAST1 Gene
EC number	2.7.11.1
Gene ontology Molecular function • magnesium ion binding • protein serine/threonine kinase activity • protein binding • ATP binding Cellular component • intracellular • cytoplasm • cytoskeleton • plasma membrane Biological process • protein phosphorylation • cytoskeleton organization • peptidyl-serine phosphorylation • intracellular signal transduction Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	22983	56527
Ensembl	ENSG00000105613	ENSMUSG00000053693
UniProt	Q9Y2H9	Q9R1L5
RefSeq (mRNA)	NM_014975	NM_019945
RefSeq (protein)	NP_055790	NP_064329
Location (UCSC)	Chr 19: 12.83 – 12.87 Mb	Chr 8: 84.91 – 84.94 Mb
PubMed search

Microtubule-associated serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MAST1 gene.^[1]

References

1. "Entrez Gene: MAST1 microtubule associated serine/threonine kinase 1".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
• Yano R, Yap CC, Yamazaki Y, et al. (2003). "Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions.". Neuroscience 117 (2): 373–81. doi:10.1016/S0306-4522(02)00785-6. PMID 12614677.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dehal P, Predki P, Olsen AS, et al. (2001). "Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution.". Science 293 (5527): 104–11. doi:10.1126/science.1060310. PMID 11441184.
• Lumeng C, Phelps S, Crawford GE, et al. (1999). "Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.". Nat. Neurosci. 2 (7): 611–7. doi:10.1038/10165. PMID 10404183.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.