Thiethylperazine
 | |
| Systematic (IUPAC) name | |
|---|---|
|
2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine | |
| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pharmacokinetic data | |
| Protein binding | 60% |
| Identifiers | |
| CAS Number |
1420-55-9  |
| ATC code | R06AD03 (WHO) |
| PubChem | CID 5440 |
| IUPHAR/BPS | 7306 |
| DrugBank |
DB00372 |
| ChemSpider |
5245 |
| UNII |
8ETK1WAF6R |
| KEGG |
D02354 |
| ChEBI |
CHEBI:9544 |
| ChEMBL |
CHEMBL1378 |
| Chemical data | |
| Formula | C22H29N3S2 |
| Molar mass | 399.618 g/mol |
| |
| |
| (verify) | |
Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.
Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice.[1]
References
- ↑ Science Daily (September 1, 2011). "Alzheimer Disease: Transport Protein ABCC1 Plays Key Role in Clearing Beta-Amyloid from Brains of Mice.". Retrieved September 1, 2011.
| ||||||||||||||||||
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||
This article is issued from Wikipedia - version of the Sunday, April 03, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.