MYH1

Myosin, heavy chain 1, skeletal muscle, adult

PDB rendering based on 1m8q.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols MYH1 ; HEL71; MYHSA1; MYHa; MyHC-2X/D; MyHC-2x
External IDs OMIM: 160730 MGI: 1339711 HomoloGene: 133718 GeneCards: MYH1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 4619 17879
Ensembl ENSG00000109061 ENSMUSG00000056328
UniProt P12882 Q5SX40
RefSeq (mRNA) NM_005963 NM_030679
RefSeq (protein) NP_005954 NP_109604
Location (UCSC) Chr 17:
10.49 – 10.52 Mb
Chr 11:
67.2 – 67.22 Mb
PubMed search

Myosin-1 is a protein that in humans is encoded by the MYH1 gene.[1][2]

Myosin is a major contractile protein that converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals, at least ten different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.[2]

References

Further reading

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