MYO1B

Myosin IB
Identifiers
Symbols	MYO1B ; myr1
External IDs	OMIM: 606537 MGI: 107752 HomoloGene: 7856 GeneCards: MYO1B Gene
Gene ontology Molecular function • microfilament motor activity • calmodulin binding • ATP binding • phosphatidylinositol-4,5-bisphosphate binding • phosphatidylinositol-3,4,5-trisphosphate binding • actin-dependent ATPase activity • actin filament binding Cellular component • cytoplasm • early endosome • actin filament • plasma membrane • brush border • endosome membrane • myosin complex • filopodium • trans-Golgi network membrane • perinuclear region of cytoplasm • extracellular exosome • cell periphery Biological process • post-Golgi vesicle-mediated transport • actin filament organization • metabolic process • actin filament-based movement • actin filament bundle assembly Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4430	17912
Ensembl	ENSG00000128641	ENSMUSG00000018417
UniProt	O43795	P46735
RefSeq (mRNA)	NM_001130158	NM_001161817
RefSeq (protein)	NP_001123630	NP_001155289
Location (UCSC)	Chr 2: 191.25 – 191.43 Mb	Chr 1: 51.75 – 51.92 Mb
PubMed search

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene.^[1][2][3]

References

1. Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.
2. Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751. PMID 8449985.
3. "Entrez Gene: MYO1B myosin IB".

Further reading

• Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell. Sci. 108 (12): 3775–86. PMID 8719884.
• Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. doi:10.1016/S0960-9822(01)00320-7. PMID 11509238.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438. PMID 12486594.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell. Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID 16219689.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.