AQP8
| Aquaporin 8 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | AQP8 ; AQP-8 | ||||||||||||
| External IDs | OMIM: 603750 MGI: 1195271 HomoloGene: 68166 IUPHAR: 695 GeneCards: AQP8 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 343 | 11833 | |||||||||||
| Ensembl | ENSG00000103375 | ENSMUSG00000030762 | |||||||||||
| UniProt | O94778 | P56404 | |||||||||||
| RefSeq (mRNA) | NM_001169 | NM_001109045 | |||||||||||
| RefSeq (protein) | NP_001160 | NP_001102515 | |||||||||||
| Location (UCSC) |
Chr 16: 25.22 – 25.23 Mb |
Chr 7: 123.46 – 123.47 Mb | |||||||||||
| PubMed search | |||||||||||||
Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene.[1][2][3]
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.[3]
See also
References
- ↑ Koyama N, Ishibashi K, Kuwahara M, Inase N, Ichioka M, Sasaki S, Marumo F (Jan 1999). "Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene". Genomics 54 (1): 169–72. doi:10.1006/geno.1998.5552. PMID 9806845.
- ↑ Viggiano L, Rocchi M, Svelto M, Calamita G (Jul 1999). "Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12". Cytogenet Cell Genet 84 (3–4): 208–10. doi:10.1159/000015260. PMID 10393433.
- 1 2 "Entrez Gene: AQP8 aquaporin 8".
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Harrington DJ, Adachi K, Royer WE (1997). "The high resolution crystal structure of deoxyhemoglobin S". J. Mol. Biol. 272 (3): 398–407. doi:10.1006/jmbi.1997.1253. PMID 9325099.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Fischer H, Stenling R, Rubio C, Lindblom A (2003). "Differential expression of Aquaporin 8 in human colonic epithelial cells and colorectal tumors". BMC Physiol. 1: 1. doi:10.1186/1472-6793-1-1. PMC 32180. PMID 11231887.
- Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Wang S, Kallichanda N, Song W, et al. (2001). "Expression of aquaporin-8 in human placenta and chorioamniotic membranes: evidence of molecular mechanism for intramembranous amniotic fluid resorption". Am. J. Obstet. Gynecol. 185 (5): 1226–31. doi:10.1067/mob.2001.117971. PMID 11717661.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wang S, Chen J, Au KT, Ross MG (2003). "Expression of aquaporin 8 and its up-regulation by cyclic adenosine monophosphate in human WISH cells". Am. J. Obstet. Gynecol. 188 (4): 997–1001. doi:10.1067/mob.2003.214. PMID 12712100.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zahn A, Moehle C, Langmann T, et al. (2007). "Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis". World J. Gastroenterol. 13 (11): 1687–95. PMID 17461471.
External links
- AQP8 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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