KCNK15
| Potassium channel, two pore domain subfamily K, member 15 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | KCNK15 ; K2p15.1; KCNK11; KCNK14; KT3.3; TASK-5; TASK5; dJ781B1.1 | ||||||||||||
| External IDs | OMIM: 607368 MGI: 2675209 HomoloGene: 11179 IUPHAR: 524 GeneCards: KCNK15 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 60598 | 241769 | |||||||||||
| Ensembl | ENSG00000124249 | ENSMUSG00000035238 | |||||||||||
| UniProt | Q9H427 | B2RVL1 | |||||||||||
| RefSeq (mRNA) | NM_022358 | NM_001030292 | |||||||||||
| RefSeq (protein) | NP_071753 | NP_001025463 | |||||||||||
| Location (UCSC) |
Chr 20: 44.75 – 44.75 Mb |
Chr 2: 163.85 – 163.86 Mb | |||||||||||
| PubMed search | |||||||||||||
Potassium channel subfamily K member 15 is a protein that in humans is encoded by the KCNK15 gene.[1][2][3][4]
This gene encodes K2P15.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P15.1 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity.[4]
See also
References
- ↑ Kim D, Gnatenco C (Jun 2001). "TASK-5, a new member of the tandem-pore K(+) channel family". Biochem Biophys Res Commun 284 (4): 923–30. doi:10.1006/bbrc.2001.5064. PMID 11409881.
- ↑ Vega-Saenz de Miera E, Lau DH, Zhadina M, Pountney D, Coetzee WA, Rudy B (Jun 2001). "KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1". J Neurophysiol 86 (1): 130–42. PMID 11431495.
- ↑ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.
- 1 2 "Entrez Gene: KCNK15 potassium channel, subfamily K, member 15".
Further reading
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
- Karschin C, Wischmeyer E, Preisig-Müller R, et al. (2002). "Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system". Mol. Cell. Neurosci. 18 (6): 632–48. doi:10.1006/mcne.2001.1045. PMID 11749039.
- Ashmole I, Goodwin PA, Stanfield PR (2002). "TASK-5, a novel member of the tandem pore K+ channel family". Pflugers Arch. 442 (6): 828–33. doi:10.1007/s004240100620. PMID 11680614.
External links
- KCNK15 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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