KCNG3
| Potassium channel, voltage gated modifier subfamily G, member 3 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | KCNG3 ; KV10.1; KV6.3 | ||||||||||||
| External IDs | OMIM: 606767 MGI: 2663923 HomoloGene: 15168 IUPHAR: 558 GeneCards: KCNG3 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 170850 | 225030 | |||||||||||
| Ensembl | ENSG00000171126 | ENSMUSG00000045053 | |||||||||||
| UniProt | Q8TAE7 | P59053 | |||||||||||
| RefSeq (mRNA) | NM_133329 | NM_153512 | |||||||||||
| RefSeq (protein) | NP_579875 | NP_705732 | |||||||||||
| Location (UCSC) |
Chr 2: 42.44 – 42.49 Mb |
Chr 17: 83.59 – 83.63 Mb | |||||||||||
| PubMed search | |||||||||||||
Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene.[1][2][1] The protein encoded by this gene is a voltage-gated potassium channel subunit.[2]
References
- 1 2 Sano Y, Mochizuki S, Miyake A, Kitada C, Inamura K, Yokoi H, Nozawa K, Matsushime H, Furuichi K (Feb 2002). "Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1". FEBS Lett 512 (1-3): 230–4. doi:10.1016/S0014-5793(02)02267-6. PMID 11852086.
- 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.
Further reading
- Mederos Y Schnitzler M, Rinné S, Skrobek L; et al. (2009). "Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.". J. Biol. Chem. 284 (7): 4695–704. doi:10.1074/jbc.M808786200. PMID 19074135.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.". Proc. Natl. Acad. Sci. U.S.A. 99 (12): 7986–91. doi:10.1073/pnas.122617999. PMC 123007. PMID 12060745.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Vega-Saenz de Miera EC (2004). "Modification of Kv2.1 K+ currents by the silent Kv10 subunits.". Brain Res. Mol. Brain Res. 123 (1-2): 91–103. doi:10.1016/j.molbrainres.2004.01.004. PMID 15046870.
External links
- Kv6.3 Potassium Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
- KCNG3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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