FOXK1

Forkhead box K1
PDB rendering based on 2a3s.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2a3s​, 2d2w​
Identifiers
Symbols	FOXK1 ; FOXK1L
External IDs	OMIM: 616302 MGI: 1347488 HomoloGene: 82414 GeneCards: FOXK1 Gene
Gene ontology Molecular function • RNA polymerase II regulatory region sequence-specific DNA binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • protein binding Cellular component • nucleus • nucleoplasm • nucleolus Biological process • regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • muscle organ development • anatomical structure morphogenesis • cell differentiation • negative regulation of cell growth • negative regulation of transcription, DNA-templated • positive regulation of transcription, DNA-templated Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	221937	17425
Ensembl	ENSG00000164916	ENSMUSG00000056493
UniProt	P85037	P42128
RefSeq (mRNA)	NM_001037165	NM_010812
RefSeq (protein)	NP_001032242	NP_951031
Location (UCSC)	Chr 7: 4.68 – 4.77 Mb	Chr 5: 142.4 – 142.46 Mb
PubMed search

Forkhead box protein K1 is a protein that in humans is encoded by the FOXK1 gene.^[1][2]

References

1. Katoh M, Katoh M (Jun 2004). "Identification and characterization of human FOXK1 gene in silico". Int J Mol Med 14 (1): 127–32. doi:10.3892/ijmm.14.1.127. PMID 15202027.
2. "Entrez Gene: FOXK1 forkhead box K1".

Further reading

• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Tsai KL, Huang CY, Chang CH; et al. (2006). "Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins.". J. Biol. Chem. 281 (25): 17400–9. doi:10.1074/jbc.M600478200. PMID 16624804.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Huang JT, Lee V (2005). "Identification and characterization of a novel human FOXK1 gene in silico.". Int. J. Oncol. 25 (3): 751–7. doi:10.3892/ijo.25.3.751. PMID 15289879.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.