ZNF238

Zinc finger and BTB domain containing 18
Identifiers
Symbols ZBTB18 ; C2H2-171; MRD22; RP58; TAZ-1; ZNF238
External IDs OMIM: 608433 MGI: 1353609 HomoloGene: 21276 GeneCards: ZBTB18 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 10472 30928
Ensembl ENSG00000179456 ENSMUSG00000063659
UniProt Q99592 Q9WUK6
RefSeq (mRNA) NM_001278196 NM_001012330
RefSeq (protein) NP_001265125 NP_001012330
Location (UCSC) Chr 1:
244.05 – 244.06 Mb
Chr 1:
177.44 – 177.45 Mb
PubMed search

Zinc finger protein 238 is a protein that in humans is encoded by the ZNF238 gene.[1][2][3]

C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.[supplied by OMIM][3]

Interactions

ZNF238 has been shown to interact with DNMT3A.[4]

References

  1. Becker KG, Lee IJ, Nagle JW, Canning RD, Gado AM, Torres R, Polymeropoulos MH, Massa PT, Biddison WE, Drew PD (June 1998). "C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain". Int J Dev Neurosci 15 (7): 891–9. doi:10.1016/S0736-5748(97)00034-8. PMID 9568537.
  2. Aoki K, Ishida R, Kasai M (February 1997). "Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX". FEBS Lett 401 (2-3): 109–12. doi:10.1016/S0014-5793(96)01444-5. PMID 9013868.
  3. 1 2 "Entrez Gene: ZNF238 zinc finger protein 238".
  4. Fuks, F; Burgers W A; Godin N; Kasai M; Kouzarides T (May 2001). "Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription". EMBO J. (England) 20 (10): 2536–44. doi:10.1093/emboj/20.10.2536. ISSN 0261-4189. PMC 125250. PMID 11350943.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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