IFI35

Interferon-induced protein 35
Identifiers
Symbols	IFI35 ; IFP35
External IDs	OMIM: 600735 MGI: 1917360 HomoloGene: 4040 GeneCards: IFI35 Gene
Gene ontology Molecular function • protein binding Cellular component • nucleus • cytosol Biological process • cytokine-mediated signaling pathway • type I interferon signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3430	70110
Ensembl	ENSG00000068079	ENSMUSG00000010358
UniProt	P80217	Q9D8C4
RefSeq (mRNA)	NM_005533	NM_027320
RefSeq (protein)	NP_005524	NP_081596
Location (UCSC)	Chr 17: 43.01 – 43.01 Mb	Chr 11: 101.45 – 101.46 Mb
PubMed search

Interferon-induced 35 kDa protein is a protein that in humans is encoded by the IFI35 gene.^[1]

Interactions

IFI35 has been shown to interact with NMI^[2] and BATF.^[3]

References

1. "Entrez Gene: IFI35 interferon-induced protein 35".
2. Chen, J; Shpall R L; Meyerdierks A; Hagemeier M; Böttger E C; Naumovski L (November 2000). "Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35". J. Biol. Chem. (UNITED STATES) 275 (46): 36278–84. doi:10.1074/jbc.M006975200. ISSN 0021-9258. PMID 10950963.
3. Wang, X; Johansen L M; Tae H J; Taparowsky E J (December 1996). "IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors". Biochem. Biophys. Res. Commun. (UNITED STATES) 229 (1): 316–22. doi:10.1006/bbrc.1996.1799. ISSN 0006-291X. PMID 8954125.

Further reading

• Brown MA, Jones KA, Nicolai H, et al. (1995). "Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.". Proc. Natl. Acad. Sci. U.S.A. 92 (10): 4362–6. doi:10.1073/pnas.92.10.4362. PMC 41944. PMID 7753812.
• Bange FC, Vogel U, Flohr T, et al. (1994). "IFP 35 is an interferon-induced leucine zipper protein that undergoes interferon-regulated cellular redistribution.". J. Biol. Chem. 269 (2): 1091–8. PMID 8288566.
• Smith TM, Lee MK, Szabo CI, et al. (1997). "Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.". Genome Res. 6 (11): 1029–49. doi:10.1101/gr.6.11.1029. PMID 8938427.
• Wang X, Johansen LM, Tae HJ, Taparowsky EJ (1997). "IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors.". Biochem. Biophys. Res. Commun. 229 (1): 316–22. doi:10.1006/bbrc.1996.1799. PMID 8954125.
• Zhou X, Liao J, Meyerdierks A, et al. (2000). "Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35.". J. Biol. Chem. 275 (28): 21364–71. doi:10.1074/jbc.M003177200. PMID 10779520.
• Chen J, Shpall RL, Meyerdierks A, et al. (2000). "Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35.". J. Biol. Chem. 275 (46): 36278–84. doi:10.1074/jbc.M006975200. PMID 10950963.
• Chen J, Naumovski L (2002). "Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells.". J. Interferon Cytokine Res. 22 (2): 237–43. doi:10.1089/107999002753536211. PMID 11911807.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zhang L, Tang Y, Tie Y, et al. (2007). "The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling.". Cell. Signal. 19 (5): 932–44. doi:10.1016/j.cellsig.2006.11.002. PMID 17197158.

External links

• IFI35 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)