Zinc finger protein 165

Zinc finger protein 165
Identifiers
Symbols	ZNF165 ; CT53; LD65; ZSCAN7
External IDs	OMIM: 600834 HomoloGene: 122143 GeneCards: ZNF165 Gene
Gene ontology Molecular function • DNA binding • transcription factor activity, sequence-specific DNA binding • protein binding • metal ion binding Cellular component • nucleus Biological process • transcription, DNA-templated • regulation of transcription, DNA-templated Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7718	n/a
Ensembl	ENSG00000197279	n/a
UniProt	P49910	n/a
RefSeq (mRNA)	NM_003447	n/a
RefSeq (protein)	NP_003438	n/a
Location (UCSC)	Chr 6: 28.08 – 28.09 Mb	n/a
PubMed search		n/a

Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene.^[1][2]

Function

This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.^[2]

Interactions

Zinc finger protein 165 has been shown to interact with Ewing sarcoma breakpoint region 1^[3] and DVL2.^[3]

See also

• Zinc finger

References

1. Tirosvoutis KN, Divane A, Jones M, Affara NA (Jan 1996). "Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis". Genomics 28 (3): 485–90. doi:10.1006/geno.1995.1178. PMID 7490084.
2. "Entrez Gene: ZNF165 zinc finger protein 165".
3. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

• Lee PL, Gelbart T, West C, Adams M, Blackstone R, Beutler E (1997). "Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain.". Genomics 43 (2): 191–201. doi:10.1006/geno.1997.4806. PMID 9244436.
• Paoloni-Giacobino A, Kern I, Rumpler Y, Djlelati R, Morris MA, Dahoun SP (2001). "Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility.". Clin. Genet. 58 (4): 324–8. doi:10.1034/j.1399-0004.2000.580411.x. PMID 11076058.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein–protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

External links

• ZNF165 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.