ZNF146

Zinc finger protein 146
Identifiers
Symbols	ZNF146 ; OZF
External IDs	OMIM: 601505 MGI: 1347092 HomoloGene: 117615 GeneCards: ZNF146 Gene
Gene ontology Molecular function • DNA binding • transcription factor activity, sequence-specific DNA binding • heparin binding • zinc ion binding Cellular component • nucleus • nucleolus • cytoplasm Biological process • regulation of transcription, DNA-templated Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7705	26465
Ensembl	ENSG00000167635	ENSMUSG00000037029
UniProt	Q15072	Q8BQN6
RefSeq (mRNA)	NM_001099638	NM_011980
RefSeq (protein)	NP_001093108	NP_036110
Location (UCSC)	Chr 19: 36.21 – 36.24 Mb	Chr 7: 30.16 – 30.17 Mb
PubMed search

Zinc finger protein OZF is a protein that in humans is encoded by the ZNF146 gene.^[1][2][3]

See also

• Zinc finger

References

1. Blottiere L, Apiou F, Ferbus D, Guenzi C, Dutrillaux B, Prosperi MT, Goubin G (Oct 1999). "Cloning, characterization, and chromosome assignment of Zfp146 the mouse ortholog of human ZNF146, a gene amplified and overexpressed in pancreatic cancer, and Zfp260 a closely related gene". Cytogenet Cell Genet 85 (3–4): 297–300. doi:10.1159/000015316. PMID 10449921.
2. Hayes H, Le Chalony C, Goubin G, Mercier D, Payen E, Bignon C, Kohno K (Jul 1996). "Localization of ZNF164, ZNF146, GGTA1, SOX2, PRLR and EEF2 on homoeologous cattle, sheep and goat chromosomes by fluorescent in situ hybridization and comparison with the human gene map". Cytogenet Cell Genet 72 (4): 342–6. doi:10.1159/000134218. PMID 8641144.
3. "Entrez Gene: ZNF146 zinc finger protein 146".

Further reading

• Le Chalony C, Prospéri MT, Haluza R, et al. (1994). "The OZF gene encodes a protein consisting essentially of zinc finger motifs". J. Mol. Biol. 236 (2): 399–404. doi:10.1006/jmbi.1994.1151. PMID 8107129.
• Ferbus D, Le Chalony C, Prospéri MT, et al. (1996). "Identification, nuclear localization, and binding activities of OZF, a human protein solely composed of zinc-finger motifs". Eur. J. Biochem. 236 (3): 991–5. doi:10.1111/j.1432-1033.1996.00991.x. PMID 8665923.
• Ferbus D, Fléchon A, Muleris M, et al. (1999). "Amplification and over-expression of OZF, a gene encoding a zinc finger protein, in human pancreatic carcinomas". Int. J. Cancer 80 (3): 369–72. doi:10.1002/(SICI)1097-0215(19990129)80:3<369::AID-IJC6>3.0.CO;2-Y. PMID 9935176.
• Pibouin L, Villaudy J, Prospéri MT, Goubin G (2001). "Genomic organization and promoter identification of ZNF146, a gene encoding a protein consisting solely of zinc finger domains". Cytogenet. Cell Genet. 92 (1–2): 80–4. doi:10.1159/000056873. PMID 11306801.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ferbus D, Bovin C, Validire P, Goubin G (2003). "The zinc finger protein OZF (ZNF146) is overexpressed in colorectal cancer". J. Pathol. 200 (2): 177–82. doi:10.1002/path.1337. PMID 12754738.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Antoine K, Ferbus D, Kolahgar G, et al. (2005). "Zinc finger protein overexpressed in colon carcinoma interacts with the telomeric protein hRap1". J. Cell. Biochem. 95 (4): 763–8. doi:10.1002/jcb.20487. PMID 15838871.
• Antoine K, Prosperi MT, Ferbus D, et al. (2005). "A Kruppel zinc finger of ZNF 146 interacts with the SUMO-1 conjugating enzyme UBC9 and is sumoylated in vivo". Mol. Cell. Biochem. 271 (1–2): 215–23. doi:10.1007/s11010-005-6417-2. PMID 15881673.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• ZNF146 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.