ZNF219

Zinc finger protein 219
Identifiers
Symbols	ZNF219 ; ZFP219
External IDs	OMIM: 605036 MGI: 1917140 HomoloGene: 9504 GeneCards: ZNF219 Gene
Gene ontology Molecular function • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • DNA binding • transcription factor activity, sequence-specific DNA binding • histamine receptor activity • protein binding • metal ion binding Cellular component • nucleus • integral component of membrane Biological process • negative regulation of transcription from RNA polymerase II promoter • regulation of neurotransmitter levels • transcription, DNA-templated • regulation of transcription, DNA-templated • G-protein coupled receptor signaling pathway • negative regulation of transcription, DNA-templated Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51222	69890
Ensembl	ENSG00000165804	ENSMUSG00000049295
UniProt	Q9P2Y4	Q4VA98
RefSeq (mRNA)	NM_001101672	NM_001253694
RefSeq (protein)	NP_001095142	NP_001240623
Location (UCSC)	Chr 14: 21.09 – 21.1 Mb	Chr 14: 52.01 – 52.02 Mb
PubMed search

Zinc finger protein 219 is a protein that in humans is encoded by the ZNF219 gene.^[1][2]

References

1. Sakai T, Toyoda A, Hashimoto K, Maeda H (Sep 2000). "Isolation and characterization of a novel zinc finger gene, ZNF219, and mapping to the human chromosome 14q11 region". DNA Res 7 (2): 137–41. doi:10.1093/dnares/7.2.137. PMID 10819330.
2. "Entrez Gene: ZNF219 zinc finger protein 219".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Paces-Fessy M, Boucher D, Petit E, et al. (2004). "The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins". Biochem. J. 378 (Pt 2): 353–62. doi:10.1042/BJ20030786. PMC 1223961. PMID 14611647.
• Sakai T, Hino K, Wada S, Maeda H (2004). "Identification of the DNA binding specificity of the human ZNF219 protein and its function as a transcriptional repressor". DNA Res. 10 (4): 155–65. doi:10.1093/dnares/10.4.155. PMID 14621294.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

External links

• ZNF219 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.