OLIG1
| Oligodendrocyte transcription factor 1 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | OLIG1 ; BHLHB6; BHLHE21 | ||||||||||||
| External IDs | OMIM: 606385 MGI: 1355334 HomoloGene: 9667 GeneCards: OLIG1 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 116448 | 50914 | |||||||||||
| Ensembl | ENSG00000184221 | ENSMUSG00000046160 | |||||||||||
| UniProt | Q8TAK6 | Q9JKN5 | |||||||||||
| RefSeq (mRNA) | NM_138983 | NM_016968 | |||||||||||
| RefSeq (protein) | NP_620450 | NP_058664 | |||||||||||
| Location (UCSC) |
Chr 21: 33.07 – 33.07 Mb |
Chr 16: 91.27 – 91.27 Mb | |||||||||||
| PubMed search | |||||||||||||
Oligodendrocyte transcription factor 1 is a protein that in humans is encoded by the OLIG1 gene.[1][2]
References
- ↑ Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM (Sep 2001). "Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors". Proceedings of the National Academy of Sciences of the United States of America 98 (19): 10851–6. doi:10.1073/pnas.181340798. PMC 58563. PMID 11526205.
- ↑ "Entrez Gene: OLIG1 oligodendrocyte transcription factor 1".
Further reading
- Zhou Q, Wang S, Anderson DJ (Feb 2000). "Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors". Neuron 25 (2): 331–43. doi:10.1016/S0896-6273(00)80898-3. PMID 10719889.
- Takebayashi H, Yoshida S, Sugimori M, Kosako H, Kominami R, Nakafuku M, Nabeshima Y (Dec 2000). "Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3". Mechanisms of Development 99 (1-2): 143–8. doi:10.1016/S0925-4773(00)00466-4. PMID 11091082.
- McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening". Gene Expression Patterns 2 (3-4): 329–35. doi:10.1016/S0925-4773(02)00390-8. PMID 12617822.
- McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening". Mechanisms of Development. 119 Suppl 1: S285–91. doi:10.1016/S0925-4773(03)00130-8. PMID 14516699.
- Arnett HA, Fancy SP, Alberta JA, Zhao C, Plant SR, Kaing S, Raine CS, Rowitch DH, Franklin RJ, Stiles CD (Dec 2004). "bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS". Science 306 (5704): 2111–5. doi:10.1126/science.1103709. PMID 15604411.
- Jakovcevski I, Zecevic N (Nov 2005). "Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS". The Journal of Neuroscience 25 (44): 10064–73. doi:10.1523/JNEUROSCI.2324-05.2005. PMID 16267213.
- Goris A, Yeo TW, Maranian M, Walton A, Ban M, Gray J, Compston A, Sawcer S (Nov 2006). "Novel Olig 1-coding variants and susceptibility to multiple sclerosis". Journal of Neurology, Neurosurgery, and Psychiatry 77 (11): 1296–7. doi:10.1136/jnnp.2006.090639. PMC 2077377. PMID 16820418.
- Ruf N, Martelli M, Weschke B, Uhlenberg B (Apr 2007). "Oligodendroglial transcription factor (OLIG1 and OLIG2) mutations are not associated with Pelizaeus-Merzbacher-like leukodystrophy". American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 144B (3): 365–6. doi:10.1002/ajmg.b.30434. PMID 17171653.
- Brena RM, Morrison C, Liyanarachchi S, Jarjoura D, Davuluri RV, Otterson GA, Reisman D, Glaros S, Rush LJ, Plass C (Mar 2007). "Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer". PLoS Medicine 4 (3): e108. doi:10.1371/journal.pmed.0040108. PMC 1831740. PMID 17388669.
External links
- OLIG1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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