ZNF281

Zinc finger protein 281
Identifiers
Symbols	ZNF281 ; ZBP-99; ZNP-99
External IDs	MGI: 3029290 HomoloGene: 8270 GeneCards: ZNF281 Gene
Gene ontology Molecular function • RNA polymerase II core promoter proximal region sequence-specific DNA binding • core promoter binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • transcription factor activity, sequence-specific DNA binding • transcription corepressor activity • protein binding • sequence-specific DNA binding • transcription regulatory region DNA binding • metal ion binding Cellular component • nucleus • nucleoplasm Biological process • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • embryonic body morphogenesis • negative regulation of gene expression • negative regulation of transcription, DNA-templated • positive regulation of transcription, DNA-templated • stem cell differentiation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23528	226442
Ensembl	ENSG00000162702	ENSMUSG00000041483
UniProt	Q9Y2X9	Q99LI5
RefSeq (mRNA)	NM_001281293	NM_001160251
RefSeq (protein)	NP_001268222	NP_001153723
Location (UCSC)	Chr 1: 200.4 – 200.41 Mb	Chr 1: 136.62 – 136.63 Mb
PubMed search

Zinc finger protein 281 is a protein that in humans is encoded by the ZNF281 gene.^[1][2]

See also

• Zinc finger

References

1. Law DJ, Du M, Law GL, Merchant JL (Sep 1999). "ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression". Biochem Biophys Res Commun 262 (1): 113–120. doi:10.1006/bbrc.1999.1180. PMID 10448078.
2. "Entrez Gene: ZNF281 zinc finger protein 281".

Further reading

• Lisowsky T, Polosa PL, Sagliano A, et al. (1999). "Identification of human GC-box-binding zinc finger protein, a new Krüppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence". FEBS Lett. 453 (3): 369–374. doi:10.1016/S0014-5793(99)00754-1. PMID 10405178.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• ZNF281 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.