PHF20

PHD finger protein 20
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2LDM​, 3P8D​, 3Q1J​, 3QII​, 3SD4​
Identifiers
Symbols	PHF20 ; C20orf104; GLEA2; HCA58; NZF; TDRD20A; TZP
External IDs	OMIM: 610335 MGI: 2444148 HomoloGene: 9507 GeneCards: PHF20 Gene
Gene ontology Molecular function • DNA binding • protein binding • zinc ion binding • histone acetyltransferase activity (H4-K5 specific) • histone acetyltransferase activity (H4-K8 specific) • histone acetyltransferase activity (H4-K16 specific) Cellular component • histone acetyltransferase complex • nucleoplasm • cytoplasm • nuclear membrane • MLL1 complex Biological process • chromatin organization • transcription, DNA-templated • regulation of transcription, DNA-templated • histone H4-K5 acetylation • histone H4-K8 acetylation • histone H4-K16 acetylation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51230	228829
Ensembl	ENSG00000025293	ENSMUSG00000038116
UniProt	Q9BVI0	Q8BLG0
RefSeq (mRNA)	NM_016436	NM_172674
RefSeq (protein)	NP_057520	NP_766262
Location (UCSC)	Chr 20: 35.77 – 35.95 Mb	Chr 2: 156.2 – 156.31 Mb
PubMed search

PHD finger protein 20 is a protein that in humans is encoded by the PHF20 gene.^[1]

References

1. "Entrez Gene: PHF20 PHD finger protein 20".

Further reading

• Fischer U, Struss AK, Hemmer D, Pallasch CP, Steudel WI, Meese E (November 2001). "Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls". Clin. Exp. Immunol. 126 (2): 206–13. doi:10.1046/j.1365-2249.2001.01635.x. PMC 1906187. PMID 11703362.
• Behrends U, Schneider I, Rössler S, Frauenknecht H, Golbeck A, Lechner B, Eigenstetter G, Zobywalski C, Müller-Weihrich S, Graubner U, Schmid I, Sackerer D, Späth M, Goetz C, Prantl F, Asmuss HP, Bise K, Mautner J (August 2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries". Int. J. Cancer 106 (2): 244–51. doi:10.1002/ijc.11208. PMID 12800201.
• Pallasch CP, Struss AK, Munnia A, König J, Steudel WI, Fischer U, Meese E (November 2005). "Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survival". Int. J. Cancer 117 (3): 456–9. doi:10.1002/ijc.20929. PMID 15906353.
• Cui G, Park S, Badeaux AI, Kim D, Lee J, Thompson JR, Yan F, Kaneko S, Yuan Z, Botuyan MV, Bedford MT, Cheng JQ, Mer G (August 2012). "PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53". Nat. Struct. Mol. Biol. 19 (9): 916–24. doi:10.1038/nsmb.2353. PMC 3454513. PMID 22864287.

External links

• PHF20 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.